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Our laboratory is seeking an early-stage postdoctoral fellow to discover new downstream mediators for a novel receptor tyrosine kinase, using a unique platform of protein array screening methodology. This will be followed by validation of their biological roles and small molecules for drug targeting purpose. Our laboratory has established promising patient-derived xenografts and genetically modified mouse models that recapitulate clinical progression of epithelial carcinomas for the above screening and drug discovery purpose [Nature. 2014 Dec 3. doi: 10.1038/nature14034, Nat Rev Urol. 2012 Oct;9(10):583-94, Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2078-83, Cancer Res. 2012 Jul 1;72(13):3135-42]. The candidate must have a minimum of one first-author paper, and ideally a recent graduate (within one year) from US/North America PhD programs.

An ideal candidate will have strong expertise in one of the following areas:
1. Molecular biology of protein-protein interactions, post-translational modifications, protein domains;
2. Signal transduction;
3. Cancer Biology.

Candidate will these techniques will be desirable: Co-Immunoprecipitation and high-throughput drug screening.

Please send us your resume, cover letter indicating your research interests, PDF of your primary paper and name of three primary references….

Don't forget to mention Naturejobs when applying.

Job details

Employer:Baylor College of Medicine (BCM)

Website:https://www.bcm.edu/people/vi...

Location:Houston, TX, United States

Expires:February 28, 2015

Job type:Postdoctoral

Salary:Unspecified

Qualifications:Postgraduate - Doctorate/PhD

Employment type:Permanent

Job hours:Full-time