Open postdoctoral position at the Biozentrum of the University of Basel in Basel, Switzerland (Group Handschin).

The main focus of our research group is the characterization of the molecular mechanisms underlying the adaptations of skeletal muscle to exercise and disease. We study the function of PGC-1alpha, a transcriptional coactivator, in regulating gene expression in muscle. In our lab, we combine in vitro approaches (biochemistry, molecular biology) with cell culture (cell lines, primary muscle cells) and validate our results in mouse models in vivo. In particular, we are studying the transcriptional adaptations of skeletal muscle to external and internal stimuli and the resulting effects on systemic physiology. For this purpose, we have transgenic mouse models as well as a large range of state-of-the-art mouse phenotyping instruments at our disposal.

Requirements: Applicants should have a PhD or MD/PhD degree with a background in molecular and cell biology. Moreover, strong experience in experimental work on metabolism, mouse physiology, skeletal muscle biology, transcriptional regulation, systems approaches or bioinformatics is ideal. Selection will furthermore be based on the educational background, motivation, independence and creativity. Knowledge of English is required, German a plus.

How to apply: Please send your CV including a list of publications, statement of research interests and 2-3 letters of recommendation by email to christoph.handschin-at-unibas.ch to apply. Review of applications will begin on January 1, 2013, and will continue until the position is filled. Starting date by arrangement. Salary according to institutional guidelines.

For further information, see www.biozentrum.unibas.ch and/or contact Prof. C. Handschin.

Contact information:

Prof. Christoph Handschin

Biozentrum, Focal Area Growth and Development

University of Basel

Klingelbergstrasse 50/70

CH-4056 Basel

Switzerland

Email christoph.handschin-at-unibas.ch