SCIENCE-JOBS-DE

Implications of epigenetic modification of circadian genes in the airway epithelium (Lubeck)

Recent advances in chrono-biology suggests that neutrophil homeostasis in the lung is critically dependent on circadian genes. Viral infections are identified to be critical in asthma pathogenesis (e.g. exacerbation) and epidemiological evidence has linked neutrophil inflammation of the lung to more severe phenotypes of asthma. It is however not well understood how host-environment interaction may alter the epigenetic regulation of circadian genes involved in lung inflammation. This project seeks to investigate epigenetic modifications of circadian genes after viral infections of airway epithelial cells.

The following skill set is desirable

Tissue culture, molecular biology (RT-PCR, Western Blot), DNA and RNA extraction, experience with viral vectors Extended experience in bioinformatics and systems biology Excellent English skills

If you are interested, we invite you to send us your application, including

Letter of interest
CV (including two referees e.g. former supervisor) Official University transcript (M.S., Diploma etc.)

The position includes

Salary equivalent according to TV-L 13 (50%) Integration into existing Junior Research Cluster and
graduate school structures on campus Inspiring translational research environment of the German Center for Lung Research (DZL, BMBF)
 Fixed term contract (31.12.2018) with optional extension

Please send your complete electronic application to Katja Berg (katja.berg@uksh.de); Closing date: 31.10.2016 For research specific questions please contact
Dr. rer. nat. Markus Weckmann (markus.weckmann@uksh.de)
For more information please see:
http://www.kinderklinik-luebeck.de/kinderpneumologie/


Markus Weckmann
markus.weckmann@uksh.de
Sektion PƤdiatrische Pneumologie und Allergologie, UniversitƤt zu Lubeck
Lubeck

Ansprechpartner: Katja Berg, katja.berg@uksh.de